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							 Hepatitis B  
Prevalence of hepatitis B infection
  
Hepatitis B virus (HBV) infection occurs throughout the world. It is estimated that more than 2 billion people have been infected, of which more than 350 million have chronic life-long hepatitis B infection. In Southeast Asia including Hong Kong, the overall prevalence of chronic hepatitis B infection is high (>8%).  Carriers of HBV are at increased risk of developing cirrhosis and hepatocellular carcinoma (HCC). Some of them are high-risk groups for HCC.high-risk groups for HCC.
  
High-risk groups for HCC, including:
 
	- Asian men over 40 years of age
	
 - Asian women over 50 years of age
	
 - Persons with cirrhosis
	
 - Persons with a family history of HCC
	
 - Carriers with persistent or intermittent alanine aminotransferase (ALT) elevation
	
 - Carriers with persistent or intermittent high HBV DNA level
	
 - Persons with heavy alcohol consumption
	
 - Smokers
  
 
About 5-10% of infected adults and 70-90% of infected infants are not able to clear the virus, therefore becoming chronic carriers and serving as a source of infection to others. 
 
									
Transmission of HBV
  
HBV is transmitted through: 
	- Perinatal transmission from infected mother to baby
	
 - Blood or body fluids contact of an infected person
	
 - Unprotected sexual contact with a carrier
  
Casual contacts, such as, shaking hands and eating at the same table do not cause hepatitis B infection. 
 
Symptoms of hepatitis B infection
  
If symptoms occur, they might include: 
	- Mild fever
	
 - Tiredness
	
 - Nausea and vomiting
	
 - Abdominal pain
	
 - Jaundice (yellowing of the skin and eyes)
	
 - Dark urine
  
Prevention of hepatitis B infection 
	- Get vaccinated for hepatitis B
	
 - Handle an open wound carefully; make sure it is properly bandaged
	
 - Do not share personal care items, e.g. razors, toothbrushes and needles
	
 - Practice safer sex and use condoms properly
  
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